An Adaptive Learning Approach To Parameter Estimation For Hybrid Petri Nets In Systems Biology

Adaptive Learning Approach To Parameter Estimation For Hybrid Petri Nets In Systems Biology

Petri nets (HPNs) that can model biological systems. In particular, based on a state space formulation we develop a decisionaided adaptive gradient descent (DAAGD) algorithm capable of cost-effectively estimating the parameters used in an HPN model. Contrary to standard gradient descent techniques, the DAAGD algorithm does not require prior knowledge, i.e., information about the discrete […]

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