Today marks a pivotal moment in Clinomic’s journey as we proudly announce the inauguration of our Clinomic AI Lab, spearheaded by Head of Technology Ahmed Hallawa, a gifted researcher and early associate of the company. This milestone is not just an accomplishment but also a realization of a long-cherished vision. From the inception of Clinomic, […]
SSMs are a useful modelling tool in systems biology and medicine. While models in these disciplines are traditionally hand-crafted, an automated generation based on experimental data becomes a topic of research interest. In particular, our goal was to classify measured processes using the generated models. An innovative likelihood-based adaptive learning approach capable of learning the […]
Medical guidelines have a significant role in the field of evidence-based medical treatment. The content of a medical guideline is based on a systematic review of clinical evidence with instructions and recommendations that clinicians can refer to. Most of the guidelines are available in an unstructured text format. Hence, clinicians must take a considerable time […]
The fast growing digitalization of medicine has facilitated the collection of patient data in databases. A smart city must facilitate such databases in its hospitals. However, handling this big data requires new strategies for filtering and processing such high volumes of patient data. In this regard, Machine Learning (ML) algorithms are increasingly applied to support […]
Sepsis is one of the leading causes of death in Intensive Care Units (ICU) world-wide. Continuous Petri Nets (CPNs) offer a promising solution in modelling its underlying, complex pathophysiological processes. In this work, we propose a framework to evolve CPNs, i.e. evolve its places, transitions, arc weights, topology, and kinetics. This facilitates modeling complex biological […]
Life-threatening cardiomyopathy is a severe, but common, complication associated with severe trauma or sepsis. Several signaling pathways involved in apoptosis and necroptosis are linked to trauma- or sepsis-associated cardiomyopathy. However, the underling causative factors are still debatable. Heparan sulfate (HS) fragments belong to the class of danger/damage-associated molecular patterns liberated from endothelial-bound proteoglycans by heparanase […]